The Long Read Sequencing Market in North America is expected to grow from US$ 570.24 million in 2021 to US$ 2,254.97 million by 2028; it is estimated to grow at a CAGR of 21.7% from 2021 to 2028.

North America Long Read Sequencing Market Overview

Five years ago, genomic sequencing was primarily confined to research settings. Today, it is rapidly becoming a cornerstone of clinical practice. Over the next five years, healthcare systems are expected to generate genomic data from more than 60 million patients. This shift has been bolstered by substantial government investment—exceeding US$4 billion across at least 14 countries—fueling national genomic medicine initiatives. These programs are driving transformative change in real-world healthcare environments by addressing implementation challenges, building evidence for broader adoption, and significantly contributing to North America Long Read Sequencing Market growth.

North America Long Read Sequencing Market Introduction

North America currently represents the largest market for long read sequencing, with the United States holding the leading share, followed by Canada. The region's market expansion is driven by rising demand for gene synthesis techniques among biopharmaceutical and biotechnology companies, active participation from key industry players, and robust R&D efforts by academic and research institutions. In addition, the increasing integration of advanced genomic methods in healthcare, along with strong government and private sector initiatives to promote precision medicine, are expected to generate substantial revenue and further stimulate growth in the North America Long Read Sequencing Market.

The surge in government funding and private investment into genomic research, especially in response to the COVID-19 pandemic, has also significantly boosted the region's market growth. Long read sequencing's unique advantages, such as improved accuracy in identifying complex genetic variants, are key drivers in its growing adoption across North America.

Impact of COVID-19: North America Long Read Sequencing Market

The United States was significantly impacted by the COVID-19 pandemic, experiencing one of the highest case rates globally. The healthcare sector underwent considerable transformation, with an intensified focus on genomic surveillance and disease tracking. Scientists have increasingly collaborated to share genomic sequence data, which has become vital for diagnosing and managing the disease. In response to the emergence of new variants, the US has ramped up its genomic sequencing efforts.

Despite initially ranking 43rd globally in sequencing efforts—sequencing only 3% of samples according to the GISAID Initiative—the US has since expanded its capabilities. For example, in April 2020, Genome Canada launched the Canadian COVID Genomics Network (CanCOGeN), a $40 million initiative. This program united Genome Canada with six regional genome centers, CGEn sequencing hubs, public health labs, universities, hospitals, and private sector partners to scale up COVID-19 genomic research both nationally and internationally.

Additionally, companies like Pacific Biosciences of California, Inc. and Labcorp collaborated to develop large-scale sequencing assays using the Sequel II system, aiming to decode thousands of SARS-CoV-2 genomes from patient samples. These developments underscore the growing demand for long read sequencing in North America, positioning the region for continued market expansion.

North America Long Read Sequencing Market Segmentation

North America Long Read Sequencing Market -By Technology

  • Single-Molecule Real-Time Sequencing (SMRT)
  • Nanopore Sequencing
  • Loop Genomics Long-Read Sequencing

North America Long Read Sequencing Market -By Product

  • Instruments
  • Consumables
  • Services

North America Long Read Sequencing Market -By Application

  • Identification and fine mapping of structural variation
  • Tandem Repeat Sequencing
  • Pseudogene discrimination
  • Resolving allele phasing
  • Reproductive genomics
  • Cancer
  • Viral and Microbial Sequencing
  • Others

North America Long Read Sequencing Market -By Workflow

  • Pre-sequencing
  • Sequencing
  • Data Analysis

North America Long Read Sequencing Market -By End User

  • Academic Research Institutes
  • Hospitals and Clinics
  • Pharma and Biotechnology Companies

North America Long Read Sequencing Market -By Country

  • US
  • Canada
  • Mexico

North America Long Read Sequencing Market -Company Profiles

  • Bionano Genomics
  • F. HOFFMANN-LA ROCHE LTD.
  • Illumina, Inc.
  • Oxford Nanopore Technologies
  • Pacific Biosciences of California, Inc.
  • PerkinElmer, Inc.
  • Quantapore, Inc.

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Author's Bio:

Suryakant Gadekar

Senior Market Research Expert at Business Market Insights